Course Descriptions
Here you can find descriptions of courses from the M.S. in Biohazardous Threat Agents & Emerging Infectious Diseases; Online Graduate Certificate in Biohazardous Threat Agents & Emerging Infectious Diseases; and M.S. in Microbiology & Immunology.
BHTA
BHTA 6515 Microbiology of Biological Threat Agents & Emerging Infectious Diseases
This course will examine threats to the US homeland, how they might evolve over the next ten years, and the consequent implications for technology and homeland security. The course will examine the motivations of non-state actors to threaten the US homeland, how those actors might use technology and exploit vulnerabilities to attack the US, and the role of technology in countering these threats and securing the homeland.
BHTA 6517 Bioterrorism
This course will examine the use of biological weapons. Terrorism in its modern form will be discussed as well as which biological agents are most likely to be used, their techniques for deployment, and their prevention and control. Specific disease agents to be covered will include anthrax, plague, botulism, smallpox, tularemia, and viral hemorrhagic fevers.
BHTA 6520 Agroterrorism
This course will cover historical and contemporary aspects of intentional introduction of microbial and chemical agents in the food chain with specific emphasis on animal viruses like foot-and-mouth disease, mad cow, Rift Valley fever, hog cholera, highly pathogenic avian influenza West Nile, and New Castle Disease. Plant pathogens, such as soybean rust will be covered. Moreover, animal and plant agent lists will be discussed to include human crossover agents. Discussions relevant to first responders will be detailed.
BHTA 6524 Emerging & Re-emerging Infectious Diseases: A Multidisciplinary Approach
This course will provide a multidisciplinary introduction to emerging and re-emerging infectious diseases that pose a threat to public, animal and environmental health. The course covers a variety of topics (disease emergence drivers, vector-borne diseases, vaccine preventable diseases, impacts of epidemics/pandemics on health systems, international health frameworks and governance) and will aim to be as current as possible, discussing disease events in real time. We believe it is important to have a foundation in a number of key topics that will be covered across a number of lectures, case studies, group discussion and assignments. By the end of this course, you will be able to: Explain the multidisciplinary dimensions that contribute to the emergence of infectious diseases; Describe synergies between climate change, land use, globalization, migration and other that drive or otherwise impact disease emergence and/or re-emergence; Understand why the global population is at risk of vector-borne diseases and illustrate how control measures are applied to reduce transmission and burden; Define health systems strengthening and outline impacts of epidemics and pandemics one health systems resilience; Explain why vaccine preventable disease continue to pose problems for health systems and why some eradication programs have been unsuccessful; Outline governance and response initiatives to address emerging and re-emerging infectious disease threats and their evidence base.
BHTA 6525 Homeland Security
This course will examine threats to the U.S. homeland and how these threats are defeated in the context of “homeland security.” The course focuses on homeland security policy and planning considerations at all levels of government (federal, state, and local) and the U.S. private sector. We place emphases on understanding the concept of risk management as well as the role of science and technology in homeland security. We will begin most classes with a review of current events before covering the material for the week. Many classes will also have guest speakers who are experts in their fields. The major assignments include an issue memo, a class exercise, and a final paper.
BHTA 6526 The Chemistry of War
This class will provide a basic knowledge of chemical warfare agents and will focus on the intended effects of chemical agents and delivery systems. The class will review historical and recent case studies of chemical warfare (CW) use and international responses, looking at the impact of these events and responses through the lens of the adversary, third parties, and Western governments. This class will feature a midterm paper, class exercises, and a final exam. Please note that this is not a chemistry class. This course is intended to push students to think critically about how chemical attacks have broken norms against weapons of mass destruction and how these developments shape the outlook for counterproliferation of chemical weapons. By the end of this course, students will be able to:
- The Chemistry and Production: Recognize different types of CW agents; focusing on their physical properties and physiological effects. Conceive general production routes and required materials.
- The Delivery and Employment: Consider military munitions, to include strategic and tactical systems, as well as improvised and small-scale delivery systems. Assess historical and current uses of these devices by states and non-state actors.
- The Threat Assessment and Political Picture: Discuss the strategic and tactical threats and values of CW agents; explore potential future for CW agents. Examine the political landscape of arms control agreements and explore international efforts to re-establish CP norms.
BHTA 6551 Biohazardous Threat Agents & Emerging Infectious Diseases Seminar
This seminar will present a variety of nationally and globally recognized experts in the broad field of biohazardous threat agents and emerging infectious diseases. Individual topics will vary depending on the expertise of each speaker. Previous lectures have included: D.A. Henderson: “From global smallpox eradication to biodefense” David Kaplan: “Aum Shinrikyo” Jeffrey Taubenberger: “Recovering the 1918 flu virus” Don Burke: “Tracking new retroviruses in Central Africa” Chad Roy: “Threat of aerosolized agents”
BHTA 6577 Defense Threat Reduction Initiatives
This elective course is focused on exploring the various aspects of how the US government, specifically the Department of Defense, works to safeguard America and its allies from weapons of mass destruction (chemical, biological, radiological, nuclear, and high yield explosives) by providing capabilities to reduce, eliminate, and counter the threat, and to mitigate its effects. An initial analysis of the current and potential nuclear/radiological, biological and chemical threat will set the stage; and the medical effects of these weapons will be briefly reviewed. Various threat reduction strategies and their medical consequences including the Chemical Weapons Convention and the Strategic Arms Reduction Treaty will be surveyed. Moreover, elimination efforts such as the Chemical Demilitarization Program will be covered. Public health and medical consequences related to the enormous task of mitigating the effects of a WMD will be covered. The course will consist primarily of lecture/discussion format with readings designed to enhance student knowledge and provoke discussion; and subject matter experts from various government agencies will present their respective roles in this realm.
BHTA 6700 AI: Health, Defense, Ethics and Policy
This course is taught with lectures 50% and discussions 50%. The first hour introduces a specific AI technology by an expert, and the second hour discusses how to regulate the specific technology. The course is taught by faculty members with interdisciplinary backgrounds in AI, health care, defense, ethics and biomedical science policy with decades of experience. Both instructors have advised at a US federal agency, teamed with an international expert in biomedical technology and the healthcare economy. In 2023, AI faced a new paradigm shift that brought much concern to AI technologies, mainly due to concerns about using the chat GPT in the educational system. However, AI has revolutionized patient care and scientific research in health care and health science.
We hope students will learn about AI in biomedical fields and defense capabilities in this course. At the same time, we will discuss how to fine-tune policies considering ethical concerns and racial and other discrimination. Due to AI, medical imaging has accelerated the diagnostic processes for discovering hidden cancers. The drug-designing process has become much more rapid and enhanced with AI. As we need to process big data in biomedical sciences, we cannot manage without the help of AI tools. Chimeric antigen receptor (CAR) T-cell therapy for cancers is a revolutionary approach to targeted, personalized immunotherapy for cancer patients; despite many advances through AI technologies, the accuracy of AI work has still not reached 100%, and there are hidden biases in AI technologies. Especially young generations need to understand the inside of the “black box” before fully taking advantage of the technologies. In this course, while introducing various AI technologies, we will discuss ethics, policy, and concerns about fully regulating these technologies to utilize their capacities.
BHTA 6715 Nuclear Weapons, Nuclear Power, & Nonproliferation
Nuclear Weapons, Nuclear Power and Non-proliferation is a graduate course that examines the most prominent weapon of mass destruction, the atomic weapon and explains how nuclear weapons and nuclear technology risk compares to biothreats and emerging infectious diseases. The course provides the context concerning other WMD risks. The course has five content units. The first unit introduces nuclear weapons and material. Unit 2 explains nuclear weapons their construction and delivery. Content Unit 3 presents the components and distribution of nuclear power. Unit 4 discusses the international norms that exist to control nuclear weapons and material. Unit 5 addresses nonproliferation and counterproliferation efforts and the reasons to do so.
BHTA 6741 Policy & Pandemic Management
This class will examine the policy landscape important for emergency management; including the lessons learned and new directions in public, animal, and plant health policies resulting from previous nationally significant epidemics and pandemics. Topics will span all levels of Federal, State, Local, Tribal, and Territorial (FSLTT) government policies and international frameworks, as possible, to give students a perspective on the ways in which policies at each level rely on coordination to affect the best outcome. Perspectives will be captured from these levels to identify and understand how strengths and shortcomings in past pandemic management can inform future emergencies from a One Health perspective.
BHTA 6803 Biosafety, Biosecurity, & Biodefense
This class will explore key elements of biosafety, biosecurity and biodefense. We will discuss how the past has influenced aspects of each discipline while focusing our efforts on their evolution in the current health security landscape. BHTA 6803 will examine current issues in biosafety, biosecurity, and biodefense – the invisible threat that touches our lives every day. What works, what doesn’t work in biosafety, biosecurity and biodefense, and why these issues are important to everyone. The course covers an introduction to the unique safety and security concerns associated with biological science and requisite capabilities, means, and methods to mitigate those concerns. Biosafety, Biosecurity and Biodefense lays a foundation to understand and assess threats and risks to and from biological materials, technology, and information.
- Articulate current issues in contemporary biodefense and understand its relationship to BW programs.
- Describe how human threat behavior and advances in biotechnology impact the assessment of biosecurity risk.
- Analyze national biosecurity, biosafety, biorisk management, and biodefense policy and discuss the degree to which goals and objectives address or fail to address the current biosecurity threat environment.
- Explain the role of biosafety and biosecurity in achieving biodefense and evaluate governance and operational requirements for safe and secure research.
BHTA 6805 Emerging Biotechnologies
Emerging technologies are transforming the life sciences. In the past decade, researchers worldwide have embraced a multidisciplinary approach that combines biological techniques, elements, and systems with engineering concepts, empowered by rapidly growing global capacities to manage and analyze complex biological data and disruptive discoveries in gene editing. Current and future technologies in the biosciences – including cellular biotechnologies, synthetic biology, and genomic medicine – have the potential to transform research, medicine, and public health, with implications for the sciences, society, and security. BHTA 6805 is a graduate seminar that will introduce the biological basis, hope, and hype of these emerging technologies through the review of current technical and policy literature. Students will prepare a policy brief with recommendations for policies and/or regulatory frameworks to balance the benefits and risks of these emerging technologies for science and society.
BHTA 7901 Border Security
Border Security: Intersection of Global Health and Biorisk Management; International Trade, Emerging Bio Threat and Trends. This graduate seminar combines presentations by experts in biosecurity and biosafety, international policy and protocols, trade and transport regulations, migratory patterns of human, livestock movements and biotechnology/dual use and criminal activity with an analysis of the primary literature in key topics in global risk of infectious diseases. You will be taught the basics of biosecurity and safety as they relate to diplomacy, intelligence, military, enforcement, economics, legislative and medical science (research, emerging epidemic events, pathogen detection, public and veterinary health). Presentations will provide an overview of global health and security issues in the context of border biohazards supported by regional or national case studies. The purpose of this seminar series is to outline possible linkages between the security and health communities, the potential for collaboration in identifying vulnerabilities and recommending viable options to more effectively secure air, sea, land, and cyber borders. These risk factors will be put into perspective from the critical relationship of Global Health, Criminal and Terrorist Activities, International Trade and Commerce, Migratory Patterns of Pathogens, Select Agents, and Pandemic Risk. The curriculum will provide expert presentation(s) on biorisk of infectious disease emergence outside the territories where they are known, as well as the regulations and strategies in place, or required, to prepare for and prevent these border transgressions. The objective of this seminar is to spur discussion to address the factors that promote biological risk at the ports of entry. Moreover, to promote collaborative strategies, policy, and regulatory protocols necessary to prevent and control such biological risk. This course uses a combination of lecture approaches, discussions, and student engagement. Students are expected to read the material provided and to be prepared to participate in all discussions. Written and oral presentations by the students, will constitute the final exam. This course is only open to Ph.D. and M.S. students in the Department of Microbiology and Immunology. This one-credit class meets every week of the semester. Seminars are held during the spring semester, with lectures focusing on concepts of border biohazards.
BHTA 7950 Internship Experience
Internships are a critical part of the academic and professional development of students in the Biomedical Policy & Advocacy and the Biohazardous Threat Agents and Emerging Infectious Diseases Masters Programs. This course allows students to enhance their professional, technical, and networking skills through a planned, supervised, and evaluated internship experience. During this 2- credit elective, the student works 60 hours, or a minimum average of 6 hours per week for 10 weeks, on-site at a sponsoring agency or organization under the direct supervision of a Site Preceptor. The internship site, specific learning objectives, and activities are determined by the student and the site preceptor, with the approval of the Course Directors. Students will work with the Course Directors to develop learning objectives for the internship. Students are expected to apply their academic knowledge and demonstrate enhancement of professional and analytical skills during the internship. The internship course is open to full-time students in their second semester of study, or those who have completed at least 12 credit hours of coursework, with at least a 3.0 (B average). Limited to Department of Microbiology and Immunology graduate students; advisor/instructor permission required.
BHTA/SYSM
BHTA/SYSM 5650 Microbiome Seminar
Microbiomics touches upon a broad range of disciplines, including microbiology, immunology, biochemistry, and bioinformatics. This new discipline can further elucidate our understanding of the complex interactions among hosts, the immune system, and health at every stage of life. This seminar series will bring leading experts in the field of microbiome and introduce students to the broad range of current research such as human immune systems, wellness and aging, environmental health, neurological functions, and population health. The course will consist of lectures by instructors and guest speakers. The course will touch upon the role of next-generation microbial sequencing, including indications for, and how to interpret the results of the taxonomic and metagenomic analyses as an introduction to the advanced course on microbiomics and health.
BSPA
BSPA 6599 Survey of International Policy
Students will learn the history and application of international policy from 1917-present, with an emphasis on understanding current events and the changing political climate. The course will focus on primary documents and sources rather than a text. Students will explore policy from the perspective of another country for the semester and will participate in discussions from the perspective of that nation.
BSPA 6606 Public Policy for Scientists
This interdisciplinary course will provide introductory lectures in a variety of fields that pertain to biomedical science policy & advocacy. Lectures will cover relevant federal agencies, prominent science advocacy groups and techniques, principles of health economics, funding of research activities, the interaction of science & industry, as well as some controversial issues in science policy such as biodefense, stem cell research, and climate change. Students will be left with a multi-faceted understanding of the environment that shapes biomedical science policy and the scientists’ role in this arena.
BSPA 7907 Biomedical Science Policy & Advocacy Capstone Project
See BSPA/BHTA 9706. All capstones aim to bridge theory and practice and are desired to impact the future professional life of students upon graduation. Students are encouraged to apply and expand the knowledge gained throughout the BSPA program as part of this process.
BSPA/BHTA
BSPA/BHTA 6589 Environmental Health & Policy
This course will prepare students in both health sciences and public policy to quickly adapt to this emerging paradigm shift, while cultivating and directing their fresh innovative ideas in areas of environmental health policy.
BSPA/BHTA 6603 Science and Technology in the Global Arena
This course is an introduction to how science and technology affect foreign affairs and how international affairs influence science and technology. It is the gateway course required of SFS juniors majoring in science, technology, and international affairs (STIA), and College science majors taking the STIA certificate. It may also be taken by undergraduates and graduate students from anywhere in the university without special permission. It has no prerequisites and is suitable both for the policy generalist and for students with backgrounds in science. The course uses examples drawn from environment, security, nuclear policy, information, communications, energy, homeland defense, health, and manufacturing technology, and explores issues of sustainability, scientific risk and uncertainty, the links of science and technology with economics and geopolitics, scientific advice to governments, and government support to research and innovation. It explores the role of technological innovation in increasing productivity and competitiveness, and in solving critical social problems.
BSPA/BHTA 6705 Seminar “Brain Initiative”: Health, Security, Ethics
The original brain initiative concept “aims to develop new high-resolution tools and data science approaches to precisely quantify behaviors and synchronize them with brain activity data, build new conceptual and computational frameworks of behavioral systems, and disseminate new tools to the research community.” This seminar series will explore various aspects of brain initiative with cutting-edge emerging technology tools and critical questions to manage multiple health and security issues using these technologies. The class consists of guest speakers investigating various brain research technologies, from advanced gut and brain axis studies to motor neuron manipulation chips and various defense capabilities. The team of instructors has a unique diversity of backgrounds, from biomedical policy to neuro-ethics to engineering. Students will learn cutting-edge brain sciences while critically evaluating these technologies from ethical points of view and creating policy proposals for appropriate regulations.
BSPA/BHTA 6710 Emerging Health Threats and Global Health Ethics
This course aims to provide a comprehensive understanding of the complex ethical dimensions of global health. It will explore ethical issues concerning three dimensions of global health: practice, policy, and research. It will address chronic and contemporary moral problems in the field by unpacking the power imbalances in worldwide health and examining the history and current practices in the field. Part 1 will provide a historical background of the evolution of global health and clarify the rationale for practicing global health ethics. Part 2 will focus on understanding the ethical issues concerning global health practice. It will present the ethical dilemmas inherent in disease-specific global health programs such as HIV, Malaria, Cancer, and the ongoing COVID-19 pandemic, focusing on unequal access to quality technologies and treatment as well as issues concerning the disproportionate burden of the diseases in LMICs. Part 3 will focus on Global health policy and governance and examine the ethical implications of the evolving global health governance landscape. The students will study the role of different global health actors in global health governance, including multilateral organizations, financial institutions like the World Bank, Civil Society Organizations, and commercial actors. They will explore issues such as ‘philanthro-capitalism’ to understand the ethical issues regarding philanthropy in global health. Part 4 will focus on ethical issues concerning global health research, evaluate the ethical dimensions of global health research and engage with concepts like ‘parachute research’ author reflexivity in addition to covering topics related to informed consent, preserving data privacy, and engaging with communities, while also contemplating the ethical obligations of investigators towards the communities they investigate. Finally, students will learn about approaches for ethical global health practice by studying models of global health accountability, such as the Framework for Tobacco Convention and People’s Health Movements. They will also read about new initiatives like the Global Health 50/50 report as an accountability mechanism for improving gender equality in global health. Students will end the course with a speculative design exercise where they will develop a model for an ethical global health system.
BSPA/BHTA 7001 Regulatory Science I: Law & Science
Please note that this course is restricted to students in the Department of Microbiology and Immunology under Biomedical Graduate Education. This includes the Ph.D. and M.S. in Microbiology and Immunology program, the M.S. in Biomedical Science Policy and Advocacy program, and the M.S. in Biohazardous Threat Agents & Emerging Infectious Diseases program. If you are a student outside of these programs who would like to take this course, please contact the program director listed on our department website for permission and for more details. If you are approved to take this course, an Add/Drop form will be required in order to add this course.
BSPA/BHTA 7003 Regulatory Science II: Law & Science
This course benefits students who desire to learn the multidisciplinary nature of regulatory science. As regulatory science covers all scientific disciplines used in the regulatory and other policymaking processes, this course provides an overview of the most frequently applied regulatory science disciplines. The course starts by giving an overview of regulatory science. Subsequently, specific fields are described. Examples of lectures include regulatory toxicology, regulatory microbiology, regulatory ecology, and other topics. The course also describes regulatory science tools such as mathematical modeling and cost-benefit analysis. Typically, uniquely qualified guest lecturers from government, academia, and industry will be invited to cover a topic and, to the extent possible, provide critical written information on the presented topic.
BSPA/BHTA 7005 Science Diplomacy & World Health
Science and health diplomacies use scientific, technological, and medical (STM) knowledge for collaborations, negotiations, and other activities among countries. These types of diplomacy aim to 1) address common international problems on STM and 2) build effective international partnerships and policies for STM. With greater globalization in business and other activities, the rapid spread of infectious diseases has become eminent, as shown in COVID-19 cases over the last three years. Thus, implementing comprehensive public health management globally, cross-border STM collaborations, and understanding cultural and national differences are crucial requirements for the world’s leaders.
BSPA/BHTA 7008 Immunogenetics in Health
This course examines in detail the unique genetics that underlie the human leukocyte antigen (HLA) system and the somatic rearrangements responsible for diversity of the T-cell and B-cell receptors. Natural killer cell receptors, transplantation genetics, the microbiome, and the genesis of cancer are surveyed. The role of adaptive immunity in control of cancer, infectious disease and autoimmunity is explored deeply.
BSPA/BHTA 7800 Global Infectious Diseases: International Perspective
This graduate seminar is a unique combination of presentations by experts in microbiology, antimicrobial drug discovery, and outbreaks of Infectious disease. Policy, public health, public opinion, research, ecology, host and vectors, and social science are united by key topics in global infectious diseases. Also, a purpose of this seminar series is for each of you to understand how Outbreaks and Anti-Microbial Resistance (AMR) require multidisciplinary approaches to intervention. The seminar series takes place in the Fall (BSPA/BHTA 7800) and the Spring (BSPA/BHTA 7801) semesters, each with different infectious diseases as a focus. BSPA/BHTA 7801 is open to all Ph.D. and M.S. students in the Department of Microbiology & Immunology and other GU graduate students. For this semester, there are two parts to the course one on Outbreaks and the other one on Anti-microbial drug resistance (AMR).
BSPA/BHTA 7801 Seminar in Global Infectious Diseases: An Interdisciplinary Perspective
This graduate seminar combines presentations by experts in microbiology & immunology, advocacy, policy, public health, infectious diseases, and social sciences with an analysis of the primary literature in key topics in global infectious diseases. The purpose of this seminar series is to address factors that influence the emergence and re-emergence of infectious diseases that affect vulnerable populations worldwide, and the drivers that either promote or prevent an effective response to these global disease burdens. Presentations will provide an overview of a Global Health issue supported by regional or national examples.
BSPA/BHTA 7906 Biomedical Science Policy & Advocacy Capstone Project
Capstone course is a term that is synonymous with ‘culmination project’ or ‘thesis.’ Capstone courses have multiple components, including oral presentations and written submissions. Students will work on their projects for the two semesters under this program. The course is hands-on, and the course director will work closely with each student, from selecting topics to research methods and presentations in front of vital policy experts. The Project provides an opportunity for students to engage in high-level inquiry focusing on an area of specialization within their professional goals. Capstone projects will be inquiry and practice-centered and draw upon areas of interest to the student from the program, such as environmental health, national security, and regulatory science. All capstones aim to bridge theory and practice and are desired to impact the future professional life of students upon graduation. Through this course, students will develop a solid foundation of “science policy-making” step by step, including critical tools (literature search, use of congress.gov, interview techniques with STM experts) and methods (standards for creating science policy proposals) that need to create a comprehensive bill proposal. The Capstone Project will demonstrate the depth and extent of knowledge of students. Students who take this course would learn every step of drafting a bill, from identifying its importance for the nations, including national security, public health, and regulations of emerging technologies to toxic substances based on environmental health and more. They will be matched with a mentor who is an expert in a specific topic a student chooses to pursue in their capstone project. They are expected to complete a substantial bill proposal with detailed references and arguments to support their bill proposal. At the end of the project, students are allowed to publish their work in a peer-reviewed journal. The course would prepare students to be policy advisors at government agencies or private thinktank.
CBTA
CBTA 6515 Microbiology of Biological Threat Agents & Emerging Infectious Diseases (Online)
This introductory course on NIH (National Institutes of Health)-designated bioterrorism agents and emerging infectious pathogens is a core requirement for students in the Biohazardous Threat Agents & Emerging Infectious Diseases certificate and MS programs. It is taught by top biodefense and bioweapons policy experts, including guest speakers, and covers both the biological and policy dimensions of biothreats. The biology component explores the structure, pathology, and virulence factors of key viral agents like Variola, Ebola, and Lassa, bacterial agents including B. anthracis (Anthrax), Yersinia pestis (Plague), or Francisella tularensis (Tularemia), as well as emerging pathogens such as Nipah, Hantavirus, and SARS. It also examines the immune responses and host-pathogen interactions associated with these agents. The policy component addresses biodefense regulations, management strategies, and oversight by organizations such as the National Science Advisory Board for Biosecurity. Students will learn about biodefense tactics used against biological threat agents and will analyze historical biothreat events to understand regulatory and policy developments. Throughout the course, the curriculum is split between biological science and policy studies, culminating in a final discussion that merges these perspectives. This closing discussion emphasizes the dual-use challenges of synthetic biology and the ethical and regulatory frameworks needed to control these materials responsibly. By integrating scientific and regulatory approaches, the course equips students with a comprehensive understanding of bioterrorism threats and the measures necessary for their management and containment. The class has lectures and tabletop exercises (group assignments). Students are expected to read all assigned materials and be prepared to participate in class discussions actively.
CBTA 6517 Bioterrorism (Online)
This graduate course provides an in-depth study of bioterrorism, focusing on the threats posed by biological weapons and the evolution of terrorism involving pathogens. It covers the history and current forms of biological terrorism, exploring the use of such weapons by both state and non-state actors. Students analyze risks linked to various pathogens, including agents like anthrax, plague, botulism, smallpox, tularemia, and viral hemorrhagic fevers. Historical case studies help students understand the motives behind biological attacks, the resources available to terrorists, and the challenges of predicting and preventing such events. Since documented cases of bioterrorism are rare, the course incorporates interactive activities – such as tabletop exercises, “red teaming” projects, and scenario-based discussions – to identify potential vulnerabilities and strategies to prevent or mitigate biological attacks. Structured into five units, the course first delves into the historical and modern aspects of terrorism, emphasizing the relevance of biological threats. The second unit reviews the historical development of biological weapons, setting a foundation for risk assessments. The third unit examines specific biological agents with the potential for weaponization. The fourth unit focuses on preparedness and response measures to lessen the impact of biological attacks. The fifth unit emphasizes current prevention and response methods, engaging students in group projects for practical learning. This comprehensive approach equips students with the interdisciplinary tools and insights needed to address the complex challenges of bioterrorism.
CBTA 6525 Homeland Security (Online)
This course examines threats to U.S. homeland security and explores strategies to counter them, focusing on the policies and planning needed at federal, state, and local government levels, as well as within the private sector. Emphasizing the importance of risk management and the role of science and technology in security, the course balances practical applications with broader strategic insights. The three-credit course meets every Friday from 4:00 to 6:30 pm, featuring discussions on current events and insights from guest experts. Major assignments include an issue memo, a class exercise, and a final paper. This policy-oriented course does not center on science or technology itself but investigates the complex strategic decisions necessary to secure the nation amid rapid technological advancements. It addresses where to allocate resources, impose restrictions, and balance policy trade-offs to achieve security objectives. Students will analyze homeland security in a multifaceted environment that considers technological proliferation and emerging policy challenges. By semester’s end, students will gain a deep understanding of essential homeland security concepts, such as risk management, border and cybersecurity, law enforcement involvement, and homeland defense. They will be able to interpret national-level events within these frameworks, perform critical policy analysis, and offer recommendations. Additionally, students will be encouraged to develop and articulate their own visions for the future of homeland security, suggesting policy measures to shape its evolution over the next decade.
CBTA 6566 Preparedness Response & Capacity (Online)
This course examines the medical impacts and response strategies for nuclear, radiological, chemical, and biological threats, with a particular focus on bioterrorism. It includes an in-depth analysis of the U.S. healthcare system’s ability to withstand a major CBRNE (chemical, biological, radiological, nuclear, and explosive) attack, using the H1N1 Pandemic Influenza as a case study to assess preparedness. The curriculum progresses from individual-level medical outcomes and treatment approaches to broader community, state, and national responses, addressing both individual therapeutic strategies and system-wide preparedness and response capabilities. In addition to exploring medical outcomes, the course evaluates the capacity for local, state, and federal response and the effect of surge capacity on biodefense readiness. It considers policy aspects related to biothreat management and the expansion of surge capacity and response capabilities, linking these to the National Strategy for Countering Biological Threats and the National Strategy for Pandemic Influenza. Delivered entirely online, the course includes reading assignments and class discussions designed to support adult learning. Course objectives include describing medical effects and treatment for biological, chemical, and nuclear threats; analyzing preparedness at various government levels; evaluating surge capacity; and examining policies for biodefense. By the end of the course, students will gain a comprehensive understanding of medical and policy responses to major CBRNE threats, equipping them to analyze and contribute to national and international biodefense strategies.
CBTA 6590 One Health and Health Security (Online)
This course will provide a comprehensive view of animal health as it relates to the concept of “One Health” for the betterment of an increasingly global society. Through lecture, students will be presented with material related to specific zoonotic diseases, such as Avian Influenza, Rabies, MERS-coV, Nipah, and West Nile, and the lessons learned through the emergence and re-emergence of these diseases in animals. Course participants will also be encouraged to follow mass media current events on relevant subject matter as a means to stimulate discussion. Other topics explored will include: the cultural and socioeconomic factors influencing human-animal interaction, the increasing interface with wild and domestic animals, animals as sentinels of human disease, and the impact of urban agriculture. The breadth of knowledge pertaining to animal health gained in this course should allow the students to apply a sharp analytical insight to very complex “Global One Health” issues.
CBTA 6595 Building Disaster Resilient Communities (Online)
This course is designed to assist graduate students interested in working in the area of public policy, social work, emergency management/business continuity, community development, healthcare/public health and environmental health to understand longstanding and emerging risks and what is required to build the capacity of communities to successfully cope with and rebound from disasters and events in an era of rapid climate, technological, and social change. The course focuses on all threats and hazards— natural and manmade, including major health threats, extreme weather, events due to technological causes and deteriorating and aging infrastructures, and cyber and physical attacks. The course will examine the fundamentals of, and requirements for community resilience and how to engage, mobilize, and enable stakeholders in communities worldwide that have different levels of resources to collaboratively identify needs and policy, planning, and technology solutions; evaluate current resilience capabilities, and devise innovative ways to fill gaps and gauge progress made. Particular attention will be paid to case studies based on recent disasters and significant events and community resilience initiatives and best practices to enable students to think critically about how the many diverse stakeholder constituencies that comprise a community can collectively address adverse health, economic, environmental, and social/human impacts of disasters and events through the interrelated domains of prevention, protection, preparedness, mitigation, response and recovery. Emphasis also will be on examining community resilience programs and activities of national, state, local, private sector and non-governmental organizations and assessing where these can be improved.
CBTA 6724 Integration of Public Health Preparedness & Emergency Management (Online)
This course will discuss the fundamentals of public health preparedness, emergency management, and the integration of the two into a cohesive preparedness and response management system.
MICB
MICB 6120 Immunology
This course covers the organs, cells, and molecules of the innate and adaptive immune system and how they contribute to discrimination of self from non-self. The paradigm is the host response to infectious agents. Hypersensitivity and autoimmunity are also considered as variations in the basic protective function of the immune system.
MICB 6140 Bacteriology & Mycology
The course is focused on principal human pathogenic bacteria and fungi. The host-pathogen relationship and antimicrobial therapy are grounded in an understanding of the structure and physiology of medically important prokaryotes and lower eukaryotes.
MICB 6190 Biology and Biochemistry of Viruses
This course covers the general principles of virology, with an emphasis on viruses that cause human disease. The course delves into the varied replication strategies of major virus families and draws connections between virus replication, disease, therapy, and prevention.
MICB 6220 Advanced Techniques in Microbiology and Immunology
Students gain hands-on experience working on cutting-edge research projects in faculty labs.
MICB 6290 Mechanism of Microbial Pathogenesis
This course explores the varied ways pathogenic bacteria overcome natural host defense, describes host responses to infection, and discusses the network of interactions between pathogen and man at the molecular and cellular level.
MICB 6600 Concepts of Immunotherapy
This course explores therapeutic approaches targeting the immune system for infections, cancer, and autoimmune diseases. It covers fundamental immunology concepts, biologics, cell-based therapies, and therapeutic vaccines. Topics include immunotherapy types, licensed and experimental small molecules, challenges, and vaccine development, featuring lectures by invited experts in immune therapy and vaccine fields.
MICB 6709 Immunogenetics: Evolution and Human Health
The course examines the evolution of immune systems over millions of years, from ancient innate systems to adaptive immunity. It details the roles played by mutation, selection, and chance in our lineage. Comparative studies cover prokaryotes to humans, including Neanderthals and Denisovans. Also explored are immune system weaknesses in autoimmunity, cancer and infectious disease and biotechnological progress in their control.
MICB 6852 Seminar in Microbiology & Immunology
This seminar series features research-based lectures on a variety of topics in the field of microbiology and immunology, given by experts from institutions around the world. External lectures are supplemented by presentations from current Ph.D. students in Microbiology & Immunology.
MICB 6853 Seminar in Microbiology & Immunology
This seminar series features research-based lectures on a variety of topics in the field of microbiology and immunology, given by experts from institutions around the world. External lectures are supplemented by presentations from current Ph.D. students in Microbiology & Immunology.
MICB 7008 Immunogenetics in Health and Disease
This course examines in detail the unique genetics that underlie the human leukocyte antigen (HLA) system and the somatic rearrangements responsible for diversity of the T-cell and B-cell receptors. Natural killer cell receptors, transplantation genetics, the microbiome, and the genesis of cancer are surveyed. The role of adaptive immunity in control of cancer, infectious disease and autoimmunity is explored deeply.
Program course requirements: